Run Fatty Run

Living in the East Coast

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Why Society Still Needs Feminism

Because to men, a key is a device to open something. For women, it’s a weapon we hold between our fingers when we’re walking alone at night.

Because the biggest insult for a guy is to be called a “pussy,” a “little bitch” or a “girl.” From here on out, being called a “pussy” is an effing badge of honor.

Because last month, my politics professor asked the class if women should have equal representation in the Supreme Court, and only three out of 42 people raised their hands.

Because rape jokes are still a thing.

Because despite being equally broke college kids, guys are still expected to pay for dates, drinks and flowers.

Because as a legit student group, Campus Fellowship does not allow women to lead anything involving men. Look, I know Eve was dumb about the whole apple and snake thing, but I think we can agree having a vagina does not directly impact your ability to lead a
college organization.

Because it’s assumed that if you are nice to a girl, she owes you sex — therefore, if she turns you down, she’s a bitch who’s put you in the “friend zone.” Sorry, bro, women are not machines you put kindness coins into until sex falls out.

Because only 29 percent of American women identify as feminist, and in the words of author Caitlin Moran, “What part of ‘liberation for women’ is not for you? Is it freedom to vote? The right not to be owned by the man you marry? The campaign for equal pay? Did all that good shit get on your nerves? Or were you just drunk at the time
of the survey?”

Because when people hear the term feminist, they honestly think of women burning bras. Dude, have you ever bought a bra? No one would burn them because they’re freaking
expensive.

Because Rush Limbaugh.

Because we now have a record number of women in the Senate … which is a measly 20 out of 100. Congrats, USA, we’ve gone up to 78th place for women’s political representation, still below China, Rwanda and Iraq.

Because recently I had a discussion with a couple of well-meaning Drake University guys, and they literally could not fathom how catcalling a woman walking down University Avenue is creepy and sexist.
Could. Not. Fathom.

Because on average, the tenured male professors at Drake make more than the tenured female professors.

Because more people on campus complain about chalked statistics regarding sexual assault than complain about the existence of sexual assault. Priorities? Have them.

Because 138 House Republicans voted against the Violence Against Women Act. All 138 felt it shouldn’t provide support for Native women, LGBT people or immigrant women. I’m kind of confused by this, because I thought LGBT people and women of color were also human beings.
Weird, right?

Because a girl was roofied last semester at a local campus bar, and I heard someone say they think she should have been more careful. Being drugged is her fault, not the fault of the person who put drugs in her drink?

Because Chris Brown beat Rihanna so badly she was hospitalized, yet he still has fans and bestselling songs and a tattoo of an abused woman on his neck.

Because out of 7 billion people on the planet, more than 1 billion women will be raped or beaten in their lifetimes. Women and girls have their clitorises cut out, acid thrown on them and broken bottles shoved up them as an act of war. Every second of every day. Every corner of the Earth.

Because the other day, another friend of mine told me she was raped, and I can no longer count on both my hands the number of friends who have told me they’ve been sexually assaulted. Words can’t express how scared I am that I’m getting used to this.

Because a brief survey of reality will tell you that we do not live in a world that values all people equally and that sucks in real, very scary ways. Because you know we live in a sexist world when an awesome thing with the name “feminism” has a weird connotation. Because if I have kids someday, I want my son to be able to have emotions and play dress up, and I want my daughter to climb trees and care more about what’s in her head than what’s on it. Because I don’t want her to carry keys between her fingers at night to
protect herself.

Because feminism is for everybody, and this is your official invitation.

Permalink ibowtonoman:

robotindisguise:

Banana Dolphins

it’s that time of year
Permalink birdsy-purplefishes:

illusoryacid:

oliviatheelf:

I never even knew this and I’ve fed bread to ducks multiple times! D: Definitely reblog this so everyone knows! 

POOR DUCKS OMG.
I PROMISE TO NEVER EVER FEED YOU BREAD EVER.

Our ducks won’t eat bread. But I guess now I know that’s a good thing.
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Permalink gofwd:

Every movie set in New York, all in one place. 
Permalink neurosciencestuff:

Scientists Find Antibody that Transforms Bone Marrow Stem Cells Directly into Brain Cells
In a serendipitous discovery, scientists at The Scripps Research Institute (TSRI) have found a way to turn bone marrow stem cells directly into brain cells.
Current techniques for turning patients’ marrow cells into cells of some other desired type are relatively cumbersome, risky and effectively confined to the lab dish. The new finding points to the possibility of simpler and safer techniques. Cell therapies derived from patients’ own cells are widely expected to be useful in treating spinal cord injuries, strokes and other conditions throughout the body, with little or no risk of immune rejection.
“These results highlight the potential of antibodies as versatile manipulators of cellular functions,” said Richard A. Lerner, the Lita Annenberg Hazen Professor of Immunochemistry and institute professor in the Department of Cell and Molecular Biology at TSRI, and principal investigator for the new study. “This is a far cry from the way antibodies used to be thought of—as molecules that were selected simply for binding and not function.”
The researchers discovered the method, reported in the online Early Edition of the Proceedings of the National Academy of Sciences the week of April 22, 2013, while looking for lab-grown antibodies that can activate a growth-stimulating receptor on marrow cells. One antibody turned out to activate the receptor in a way that induces marrow stem cells—which normally develop into white blood cells—to become neural progenitor cells, a type of almost-mature brain cell.
Nature’s Toolkit
Natural antibodies are large, Y-shaped proteins produced by immune cells. Collectively, they are diverse enough to recognize about 100 billion distinct shapes on viruses, bacteria and other targets. Since the 1980s, molecular biologists have known how to produce antibodies in cell cultures in the laboratory. That has allowed them to start using this vast, target-gripping toolkit to make scientific probes, as well as diagnostics and therapies for cancer, arthritis, transplant rejection, viral infections and other diseases.
In the late 1980s, Lerner and his TSRI colleagues helped invent the first techniques for generating large “libraries” of distinct antibodies and swiftly determining which of these could bind to a desired target. The anti-inflammatory antibody Humira®, now one of the world’s top-selling drugs, was discovered with the benefit of this technology.
Last year, in a study spearheaded by TSRI Research Associate Hongkai Zhang, Lerner’s laboratory devised a new antibody-discovery technique—in which antibodies are produced in mammalian cells along with receptors or other target molecules of interest. The technique enables researchers to determine rapidly not just which antibodies in a library bind to a given receptor, for example, but also which ones activate the receptor and thereby alter cell function.
Lab Dish in a Cell
For the new study, Lerner laboratory Research Associate Jia Xie and colleagues modified the new technique so that antibody proteins produced in a given cell are physically anchored to the cell’s outer membrane, near its target receptors. “Confining an antibody’s activity to the cell in which it is produced effectively allows us to use larger antibody libraries and to screen these antibodies more quickly for a specific activity,” said Xie. With the improved technique, scientists can sift through a library of tens of millions of antibodies in a few days.
In an early test, Xie used the new method to screen for antibodies that could activate the GCSF receptor, a growth-factor receptor found on bone marrow cells and other cell types. GCSF-mimicking drugs were among the first biotech bestsellers because of their ability to stimulate white blood cell growth—which counteracts the marrow-suppressing side effect of cancer chemotherapy.
The team soon isolated one antibody type or “clone” that could activate the GCSF receptor and stimulate growth in test cells. The researchers then tested an unanchored, soluble version of this antibody on cultures of bone marrow stem cells from human volunteers. Whereas the GCSF protein, as expected, stimulated such stem cells to proliferate and start maturing towards adult white blood cells, the GCSF-mimicking antibody had a markedly different effect.
“The cells proliferated, but also started becoming long and thin and attaching to the bottom of the dish,” remembered Xie.
To Lerner, the cells were reminiscent of neural progenitor cells—which further tests for neural cell markers confirmed they were.
A New Direction
Changing cells of marrow lineage into cells of neural lineage—a direct identity switch termed “transdifferentiation”—just by activating a single receptor is a noteworthy achievement. Scientists do have methods for turning marrow stem cells into other adult cell types, but these methods typically require a radical and risky deprogramming of marrow cells to an embryonic-like stem-cell state, followed by a complex series of molecular nudges toward a given adult cell fate. Relatively few laboratories have reported direct transdifferentiation techniques.
“As far as I know, no one has ever achieved transdifferentiation by using a single protein—a protein that potentially could be used as a therapeutic,” said Lerner.
Current cell-therapy methods typically assume that a patient’s cells will be harvested, then reprogrammed and multiplied in a lab dish before being re-introduced into the patient. In principle, according to Lerner, an antibody such as the one they have discovered could be injected directly into the bloodstream of a sick patient. From the bloodstream it would find its way to the marrow, and, for example, convert some marrow stem cells into neural progenitor cells. “Those neural progenitors would infiltrate the brain, find areas of damage and help repair them,” he said.
While the researchers still aren’t sure why the new antibody has such an odd effect on the GCSF receptor, they suspect it binds the receptor for longer than the natural GCSF protein can achieve, and this lengthier interaction alters the receptor’s signaling pattern. Drug-development researchers are increasingly recognizing that subtle differences in the way a cell-surface receptor is bound and activated can result in very different biological effects. That adds complexity to their task, but in principle expands the scope of what they can achieve. “If you can use the same receptor in different ways, then the potential of the genome is bigger,” said Lerner.
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Permalink clover-rabbit:

Let’s make an oragami pikachu!! :D

OMG
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